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Participants were women aged 55 to 74 years, 880 of them with invasive ductal breast cancer, 1027 with invasive lobular breast cancer, and 856 with no cancer serving as controls Exposures Recency and duration of use of antihypertensive medications Main Outcomes and Measures Risks of invasive ductal and invasive lobular breast cancers Jul 27, 2023 · Breast cancer risk is influenced by multiple factors, and estrogen levels play a crucial role Estrogen can stimulate breast tissue and contribute to the development and growth of breast cancer --- nature com articles s41440-023-01321-y In a recent case–control study, long-term use of calcium channel blocking drugs was associated with a greater-than-twofold increased breast cancer risk If prospectively collected data confirm that calcium channel blocker use increases breast cancer risk, this would have major implications for hypertension treatment The objective of this study was The results showed that 5 years of exposure to CCBs did not significantly increase the odds of developing breast cancer (OR, 1 1), which is similar to the effect after 5 to 9 9 years in the study by Li et al 2 However, because Li et al showed that long-term use (≥10 years) of CCBs may increase the odds of developing breast cancer, the cardiooncologyjournal biomedcentral com articles 10 1186 s40959-021-00101-2Jan 31, 2017 · In the Li et al study, CCB use for ≥10 years was associated with a 2 4-fold higher risk of ductal breast cancer (95% CI: 1 2, 4 9) and a 2 6-fold higher risk of lobular breast cancer (95% CI: 1 3, 5 3) Li et al reduced recall bias by focusing on current CCB use and had interviewers record use from participants’ prescription bottles The pathophysiology of hypertension and cancer are intertwined Hypertension has been associated with an increased likelihood of developing certain cancers and with higher cancer-related mortality Moreover, various anticancer therapies have been reported to cause new elevated blood pressure or worsening of previously well-controlled hypertension Hypertension is a well-established risk factor People also ask--- dovepress com association-of-hypertension-and-breast-cancer-antihyper The researchers found a higher risk of both lobular breast cancer (P = 04 for trend) and ductal breast cancer (P = 01 for trend) among those women who took calcium-channel blockers Both short and long-acting agents and dihydropyridines and non-dihydropyridines were associated with the risk But, other blood pressure medications-angiotensin jamanetwork com journals jamainternalmedicine fullarticle 1897546 Participants were women aged 55 to 74 years, 880 of them with invasive ductal breast cancer , 1027 with invasive lobular breast cancer , and 856 with no cancer serving as controls Exposures Recency and duration of use of antihypertensive medications Main Outcomes and Measures Risks of invasive ductal and invasive lobular breast cancers Can Gail Model predict absolute risk of invasive breast cancer? Breast cancer risk is influenced by multiple factors, and estrogen levels play a crucial role Estrogen can stimulate breast tissue and contribute to the development and growth of breast cancer Introduction Breast cancer (BC) is the most common malignancy affecting women, and its incidence in younger women is rising worldwide 1 Although significant advancements in breast cancer therapy have resulted in increased survival rates; however, owing to some clinical limitations, its prevention and prognosis yet remain a challenge all over the world 2,3 Breast cancer is the second most link springer com article 10 1007 s12609-020-00379-8The risk for breast cancer was observed to be significantly lower in patients receiving calcium channel blockers than in those receiving angiotensin converting enzyme inhibitors angiotensin II Although evidence for the benefits of antihypertensive medication in the prevention of cardiovascular disease is well established, 1 low adherence to treatment is a major barrier to effective blood pressure control 2 Non-compliance with antihypertensive medication is often due to concerns about possible adverse effects, 3 including an increased risk of developing cancer 4–7 Several jamanetwork com journals jamainternalmedicine fullarticle 1723871May 30, 2023 · The risk for breast cancer was observed to be significantly lower in patients receiving calcium channel blockers than in those receiving angiotensin converting enzyme inhibitors angiotensin II Purpose of Review What is the current evidence for the role of drugs as risk factors for the development of breast cancer–related lymphoedema (BCRL) and in exacerbating existing BCRL? What are the mechanisms by which these effects occur? Recent Findings There is now evidence that taking calcium channel blockers (CCBs) during and after breast cancer treatment and receiving docetaxel See full list on breast - cancer -research biomedcentral com --- cancernetwork com some-blood-pressure-drugs-increase-breast-cancer-risk--- thelancet com journals lanonc article PIIS1470-2045(21)00033-4 fulltext--- nature com articles s41440-023-01382-z Breast cancer is the most common nonskin cancer and the second leading cause of cancer death in women 2 In 2018, an estimated 266 120 new cases of breast cancer were diagnosed in women in the United States, representing 30% of all new cancer cases in women 2 An estimated 40 920 women in the United States died of breast cancer , representing 14 Can Gail Model predict absolute risk of invasive breast cancer? Background In a recent case–control study, long-term use of calcium channel blocking drugs was associated with a greater-than-twofold increased breast cancer risk If prospectively collected data confirm that calcium channel blocker use increases breast cancer risk, this would have major implications for hypertension treatment The objective of this study was to determine whether women using Although evidence for the benefits of antihypertensive medication in the prevention of cardiovascular disease is well established, 1 low adherence to treatment is a major barrier to effective blood pressure control 2 Non-compliance with antihypertensive medication is often due to concerns about possible adverse effects, 3 including an increased risk of developing cancer 4–7 Several breast-cancer-research biomedcentral com articles 10 1186 s13058-016-0720-6
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