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Misoprostol is a prescription drug used to reducing the risk of NSAID (nonsteroidal anti-inflammatory drugs, including aspirin)–induced gastric ulcers in patients at high risk of complications from gastric ulcer, such as the elderly and patients with concomitant debilitating disease, as well as patients at high risk of developing gastric ulceration, such as patients with a history of ulcer Misoprostol oral tablet is used to reduce the risk of stomach ulcers caused by NSAIDs Learn about side effects, warnings, dosage, and more reference medscape com drug cytotec-misoprostol-341995--- webmd com drugs 2 drug-6111 misoprostol-oral detailsMisoprostol tablets are indicated for reducing the risk of NSAID (nonsteroidal anti-inflammatory drugs, including aspirin)–induced gastric ulcers in patients at high risk of complications from gastric ulcer, e g , the elderly and patients with concomitant debilitating disease, as well as patients at high risk of developing gastric ulceration, such as patients with a history of ulcer Prophylaxis: 600 mcg PO within 1 minute of delivery Treatment: 800 mcg PO once; use caution if prophylactic dose already given and adverse effects present or observed Use only in settings where oxytocin not available Treatment of Incomplete Abortion (Off-label) 600 mcg buccally once Intrauterine Fetal Death (Orphan) Treatment of May 24, 2024 · Misoprostol reduces stomach acid and helps protect the stomach lining from damage that can be caused by taking aspirin or a nonsteroidal anti-inflammatory drug (NSAID) Misoprostol is a synthetic prostaglandin that works by "replacing" prostaglandins whose production is blocked by aspirin or NSAIDs --- drugs com misoprostol html--- rxlist com misoprostol generic-drug htmNov 30, 2022 · Usual Adult Dose for Duodenal Ulcer 200 mcg orally 4 times a day after meals and at bedtime Maintenance dose: 100 to 200 mcg orally 4 times a day Comment: Treatment should be taken for the duration of non-steroidal anti-inflammatory drug (NSAID) therapy Use: Reducing the risk of NSAID-induced gastric ulcers in patients at high risk of go drugbank com drugs DB00929--- medicine com drug misoprostol hcpSep 10, 2024 · How is misoprostol supplied ( dosage forms)? Misoprostol is available as Cytotec and generic misoprostol in the following dosage forms that are taken by mouth 100 mcg oral tablets ; 200 mcg oral Place 2 misoprostol tablets in each cheek pouch for 30 minutes and then swallow anything left over with a drink of water or another liquid The medicines may not work as well if you take misoprostol sooner than 24 hours after mifepristone or later than 48 hours after mifepristone Comments:-Pain medications should be provided Rectal (off-label route): 600 to 1,000 mcg as a single dose (ACOG 183 2017) Sublingual (off-label route): 800 mcg as a single dose Use caution if a prophylactic dose was already given, especially if adverse events were observed (FIGO 2012b) Dosage ranges of 600 to 1,000 mcg as a single dose have been noted (ACOG 183 2017), however a lower --- pfizermedicalinformation com patient cytotecJan 12, 2023 · Misoprostol tablets should be stored at a temperature of 68°F to 77°F (20°C to 25°C) in a tightly sealed container For short periods of time, such as when traveling, misoprostol tablets may Find patient medical information for Misoprostol (Cytotec) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings--- drugs com pro misoprostol htmlOther medications such as carboprost, hemabate, or oxytocin, may also be used during pregnancy termination Mifepristone (Mifeprex, RU-486) works by blocking progesterone, which is essential for a pregnancy to develop This prevents the existing pregnancy from progressing Misoprostol is then taken 24–48 hours after mifepristone --- drugs com condition abortion htmlRectal (off-label route): 600 to 1,000 mcg as a single dose (ACOG 183 2017) Sublingual (off-label route): 800 mcg as a single dose Use caution if a prophylactic dose was already given, especially if adverse events were observed (FIGO 2012b) Dosage ranges of 600 to 1,000 mcg as a single dose have been noted (ACOG 183 2017), however a lower Misoprostol is indicated as a tablet to reduce the risk of NSAID induced gastric ulcers but not duodenal ulcers in high risk patients 13 Misoprostol is also formulated in combination with diclofenac to treat symptoms of osteoarthritis or rheumatoid arthritis in patients with a high risk of developing gastric ulcers 14 Misoprostol is used off label for the management of miscarriages Pharmacodynamics Misoprostol is a prostaglandin E1 analog used to reduce the risk of NSAID induced gastric ulcers by reducing secretion of gastric acid from parietal cells 3,13,14 Misoprostol is also used to manage miscarriages and used alone or in combination with mifepristone for first trimester abortions 4,2,6 An oral dose of misoprostol has an 8 minute onset of action and a duration of Tablet 100 mcg 200 mcg Dosage Considerations – Should be Given as Follows: NSAID-Induced Ulcer Adult Prophylaxis 200 mcg orally every 6 hours with food; may be decreased to 100 mcg every 6 hours if higher dose is not tolerated; last dose to be administered at bedtime Should take therapy for duration of therapy Misoprostol, over the range of 50–200 mcg, inhibits basal and nocturnal gastric acid secretion, and acid secretion in response to a variety of stimuli, including meals, histamine, pentagastrin, and coffee Activity is apparent 30 minutes after oral administration and persists for at least 3 hours --- medicalnewstoday com articles drugs-misoprostol-tablet

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