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Jul 16, 2023 · Midodrine can cause side effects like tingling or pricking feeling and goosebumps Midodrine is available as a generic; there's no brand-name version of this medication Reviewed by: Yen Nguyen, PharmD Allison Gourley, PharmD Last reviewed on July 16, 2023 chevron_left Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron isoflurane isoflurane increases toxicity of midodrine by Mechanism: unknown Avoid or Use Alternate Drug --- rxlist com proamatine-drug htm Uses for Proamatine Midodrine is used to treat low blood pressure (hypotension) It works by stimulating nerve endings in blood vessels, causing the blood vessels to tighten As a result, blood pressure is increased This medicine is available only with your doctor's prescription ProAmatine is indicated for the treatment of symptomatic orthostatic hypotension (OH) Because ProAmatine can cause marked elevation of supine blood pressure (BP>200 mmHg systolic), it should be used in patients whose lives are considerably impaired despite standard clinical care, including non-pharmacologic treatment (such as support stockings), fluid expansion, and lifestyle alterations Itching skin High blood pressure while lying down (supine hypertension) Urinary retention, urgency, frequency Chills Pain, including abdominal stomach pain Rash Nervousness Less common side effects of midodrine include: Anxiety Is proamatine safe during pregnancy? 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