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chest pain, fast or pounding heartbeats; extreme drowsiness, feeling like you might pass out; or decreased adrenal gland hormones - nausea, vomiting, stomach pain, loss of appetite --- mdcalc com calc 10170 morphine-milligram-equivalents-mme-calculatorLoading dose: 2 5 mg Demand dose: 0 5 to 2 mg Lockout: 10-minute Maximum Dosing: Opioid Naive: 10 mg hour; Opioid Tolerant: 30 mg hour, although greater rates may be needed in select patients Epidural Administration: Initial dose: 5 mg in the lumbar region may provide satisfactory pain relief for up to 24 hours Dose-dependent conversions: The conversion ratio of certain opioids can be dependent on the dose of the original opioid In the case of converting morphine to methadone, methadone has a relative potency of 4:1 at lower morphine doses, but becomes much more potent (12:1) in patients converting from very high morphine doses 5, 7 --- drugs com cdi morphine-immediate-release-tablets-and-capsules html--- pediatriconcall com drugs morphine 783There is no completely safe opioid dose, and this calculator does not substitute for clinical judgment Use caution when prescribing opioids at any dosage, and prescribe the lowest effective dose Conversions are based on the CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, 2022 Morphine, a pure opioid agonist, is relatively selective for the mu receptor, although it can interact with other opioid receptors at higher doses In addition to analgesia, the widely diverse effects of morphine include drowsiness, changes in mood, respiratory depression, decreased gastrointestinal motility, nausea, vomiting and alterations of --- drugs com dosage morphine htmlMorphine is 35% protein bound, the metabolite morphine-3-glucuronide is 10% protein bound, and morphine-6-glucuronide is 15% protein bound 4 Metabolism Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6 4 Morphine can also be metabolized to codeine, normorphine, and morphine ethereal sulfate 6--- drugs com morphine html--- webmd com drugs 2 drug-327-9352 morphine-oral details Morphine is 35% protein bound, the metabolite morphine -3-glucuronide is 10% protein bound, and morphine -6-glucuronide is 15% protein bound 4 Metabolism Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6 4 Morphine can also be metabolized to codeine, normorphine, and morphine ethereal sulfate 6 --- webmd com drugs 2 drug-327-819 morphine-oral morphine-oral detailsAug 14, 2023 · Loading dose: 2 5 mg Demand dose: 0 5 to 2 mg Lockout: 10-minute Maximum Dosing: Opioid Naive: 10 mg hour; Opioid Tolerant: 30 mg hour, although greater rates may be needed in select patients Epidural Administration: Initial dose: 5 mg in the lumbar region may provide satisfactory pain relief for up to 24 hours Find patient medical information for morphine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings See also Warning section Nausea, vomiting, constipation, sweating, lightheadedness, dizziness, or drowsiness may occur Some of these side effects may decrease after you have been using this go drugbank com drugs DB00295
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